Saturday, December 21, 2019
Bill Gates on the incredible methods of treating Alzheimers in the near future
Bill Gates on the incredible methods of treating Alzheimers in the near futureBill Gates on the incredible methods of treating Alzheimers in the near futureTo Bill Gates, the lack of a simple method of diagnosing Alzheimers disease is one of the principal factors cementing its place as the sixth leading cause of death in the US.When a patient is initiallydiagnosed, a tournament of clinical tests and trails begins, often when its too late for these treatments to work effectively.The best weve gotThe most common means of identifying Alzheimers at present are either expensive or invasive. The first characterization is aimed at the use of brain scans, which came into common practice in the late 90s.Follow Ladders on FlipboardFollow Ladders magazines on Flipboard covering Happiness, Productivity, Job Satisfaction, Neuroscience, and moraOne of the earliest signs of Alzheimers is a build up of amyloid-Beta and tau proteins in the brain. Either CTS or MRI scans are used to determine the loss of brain mass that occurs years before cognitive decline. Why are these necessary procedures so expensive? Obtaining an image machine is merely a costly affair for hospitals, saying nothing of the fact that most doctors prefer to run as many tests as possible. Moreover, providers can charge whatever they like to, which means the prices vary significantly from practice to practice.The other standard method of identifying Alzheimers is a lumbar puncture or a spinal tap a procedure ushered in by a kollektiv of Swedish scientists back in 2006. In order to analyze the proteins associated with Alzheimers, medical professionals extract samples from the fluid that surrounds and protects the brain and spinal cord. This is a very stressful and sometimes painful procedure for patients. Both systems are regularly used even though, as Gates points out, many patients seek evaluationafter the disease is already pretty advanced. The next promising mechanism of combat against this deadly disease is ascertaining an affordable, simplistic painless way to spot symptoms as early as possible.A call for unusual approachesIn a recent blog post Gates enthusiastically declared his investment in a new fund with the Alzheimers Drug Discovery Foundation called Diagnostics Accelerator, alongsideJeff and Mackenzie Bezos. This notable partnership has put ashared objective more into focus blood tests. They have donated $15 million to date and the fund, which started in July of 2018, now has a total of $35 million in investments from a collection of partners.Not too long ago a team of researchers conducted a study that disclosed data that submitted changesin the blood in patients with Alzheimers. Independent studies that yielded similarly consistent results signify that the use of blood samples to diagnose Alzheimers might come into practice as early as one or two years from now.Gates writes, Thats super exciting because it means that labs will be able to recruit more patients more quickly, a nd scientists will be able to figure out whether a drug works in less time. It also means that youll one day be able to easily get tested during a routine doctors visit.Thats the digestible promisingstride in Alzheimers diagnosis research. Gates additionally mentions another possible way of identifying the disease early on, one that he describes as coming right out of science fiction.A meeting with a researcher named Rhoda Au, revealed a method that is perhaps not as close as blood testing in terms of actualization but inspires buoyancy all the same. Dr. Au is in charge of neuropsychology for the Framingham Heart Study, which has monitored residents of a town for more than 70 years. Some of these residents have developed Alzheimers, and apparently highlighted differences in speech patterns that energized an interesting idea. There are subtle changes in the way AD patients speak, changes meaningful enough to perhaps identify its development before advanced stages. Like many forms of malady, the earlier the diagnosis the more optimistic the prognosis.Whether are not these methods will be sufficient enough to sustain usage going forward, is not yet known. The important take away from this kind of research though, is how faithfully imagination serves diligent research and analysis. The brain is an impossibly complex organ, so it stands to reason that unorthodox tactics would be best suited to rectify cognitive atrophy. Gates writes, That deeper understanding is already benefitting Alzheimers research, and Im eager to see what other game-changing diagnostics it unlocks in the years to come.You might also enjoyNew neuroscience reveals 4 rituals that will make you happyStrangers know your social class in the first seven words you say, study finds10 lessons from Benjamin Franklins daily schedule that will double your productivityThe worst mistakes you can make in an interview, according to 12 CEOs10 habits of mentally strong people
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